An Overview of the 5-HT2 Receptor

Published on by Andrew Marshall

Introduction

The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

Outline

The 5-HT2 subfamily consists of three G protein-coupled receptors (GPCRs) which are coupled to Gq/G11 and mediate excitatory neurotransmission, including:

  • 5-HT2A
  • 5-HT2B
  • 5-HT2C

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