Introduction

Fluspirilene (Redeptin, Imap, R6218) is a diphenylbutylpiperidine typical antipsychotic drug, used for the treatment of schizophrenia.

It is administered intramuscularly.

It was discovered at Janssen Pharmaceutica in 1963.

A 2007 systematic review investigated the efficacy of fluspirilene decanoate for people with schizophrenia:

“Participant numbers in each comparison were small so power to identify clear difference is limited. Randomized controlled trial data identified no clear differences between the long-acting injection of fluspirilene and oral medication for outcomes that include adverse effects.” (Abhijnhan et al., 2007).

References

Abhijnhan A, Adams CE, David A, Ozbilen M (January 2007). “Depot fluspirilene for schizophrenia”. The Cochrane Database of Systematic Reviews. 2007 (1): CD001718. doi:10.1002/14651858.CD001718.pub2. PMC 7025783. PMID 17253464.