What is a Serotonergic Drug?

Introduction

Serotonergic means “pertaining to or affecting serotonin”.

Background

Serotonin is a neurotransmitter. A synapse is serotonergic if it uses serotonin as its neurotransmitter. A serotonergic neuron produces serotonin. A substance is serotonergic if it produces its effects via interactions with the serotonin system, such as by stimulating or blocking neurotransmission.

A serotonergic or serotoninergic agent is any chemical that modifies the effects of serotonin in the body. Some different types of serotonergics drugs include the following:

  • Serotonin receptor agonists and antagonists;
  • Serotonin reuptake inhibitors; and
  • Serotonin releasing agents.

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