Introduction

Fludiazepam, marketed under the brand name Erispan, is a potent benzodiazepine and 2ʹ-fluoro derivative of diazepam.

Refer to Difludiazepam.

Background

It was originally developed by Hoffman-La Roche in the 1960s.

It is marketed in Japan and Taiwan. It exerts its pharmacological properties via enhancement of GABAergic inhibition.

Fludiazepam has 4 times more binding affinity for benzodiazepine receptors than diazepam. It possesses anxiolytic, anticonvulsant, sedative, hypnotic and skeletal muscle relaxant properties. Fludiazepam has been used recreationally.